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Scientists Attack Telomerase
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Business New Haven
10/4/1999
By: BNH
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| Another Yale researcher has helped increase scientists' understanding of telomerase, an enzyme that makes cancer cells grow, which could lead to new ways to attack cancer with chemotherapy. The study is printed in the September 9 issue of Nature magazine and lists Sandra L. Wolin of Yale and Thomas R. Cech of the University of Colorado, who was the lead investigator. Telomerase is part of what makes a cancer cell a cancer cell and plays a key role in their reproduction. While studying yeast cells, researchers found that the telomerase enzyme assembles using a pathway that is already well known to researchers. "This makes the enzyme a more accessible target for chemotherapy," explained Wolin, associate professor of cell biology, molecular biophysics and biochemistry.
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